She is not considered close contact with either of her parents, said Michael LaRosa, a spokeswoman for the first lady. White House spokeswoman Caryn Jean-Pierre said it had been “several days” since the president and first lady last saw their daughter.

A positive Ashley Biden test was announced just before Jill Biden’s flight to Ecuador on Wednesday, the first stop on her six-day trip to Latin America. The First Lady also planned to visit Panama and Costa Rica before returning to Washington next week.

Related: COVID-19 cases among Washington brokers focus new attention on White House protocols for Biden

This is the second time the coronavirus has forced 40-year-old Ashley Biden to miss a trip abroad with her mother.

Earlier in May, she was knocked off a First Lady’s trip to Eastern Europe to visit Ukrainian refugees, after learning she was in close contact with someone who later tested positive for COVID-19. Larosa said that after this exposure Ashley Biden’s test was negative.

The Centers for Disease Control and Prevention defines “close contact” with an infected person as spending 15 minutes or more with him or her for a 24-hour period. The CDC says people with “close contact” don’t need to be quarantined if they are aware of their vaccines, but should wear well-chosen masks next to other people for 10 days after contact.